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Injectin In Vivo siRNA Delivery KitInjectin In Vivo siRNA Delivery Kit contains a new lipid-based formulation which enables the delivery of siRNA into living organisms. Injectin reagent has been especially developed for local and systemic siRNA administrations in mouse. Due to it's high efficiency and it's stability, Injectin reagent is able to maintain in vivo silencing of gene expression for a very long time, without the need of multiple injection repeats.
Main advantages
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10 µg of a luciferase siRNA were directly injected into a 100 mm3 mouse tumor 4T1 expressing luciferase by using 10 µL of Injectin reagent. The same experiment was performed by using other in vivo siRNA delivery reagents (X, Y and Z) according to manufacturer's protocols. After 8 days, tumors were excised and lysed in a protease inhibitor solution. Luciferase activities were measured with a luminometer. All data were corrected by protein concentration assays. |
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